Overview

LikelihoodProfiler is a Julia package for practical identifiability analysis and confidence intervals estimation using the profile likelihood approach. The package provides a unified interface for various profile likelihood-based methods of practical identifiability:

• Confidence intervals by Constrained Optimization method (CICO)
• Optimization-based likelihood profiles
• Integration-based likelihood profiles
• Hybrid approaches

Installation

In Julia terminal run the following command:

import Pkg; Pkg.add("LikelihoodProfiler")

Citation

Borisov I., Metelkin E. An Algorithm for Practical Identifiability Analysis and Confidence Intervals Evaluation Based on Constrained Optimization. 2018. October. ICSB2018. https://doi.org/10.13140/RG.2.2.18935.06563